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EMD-41417
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex
EMD-41417
Single-particle3.61 Å
Deposition: 01/08/2023Map released: 08/05/2024
Last modified: 18/12/2024
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens,
Homo sapiens
Sample: Complex between HIV-1 Env BG505 DS-SOSIP and Bi-specific antibody CAP256L-R27
Fitted models: 8tni
Deposition Authors: Zhou T
,
Morano NC,
Roark RS,
Kwong PD ,
Xu J
Sample: Complex between HIV-1 Env BG505 DS-SOSIP and Bi-specific antibody CAP256L-R27
Fitted models: 8tni
Deposition Authors: Zhou T
,
Morano NC,
Roark RS,
Kwong PD ,
Xu J
Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
Xu J ,
Zhou T ,
McKee K,
Zhang B,
Liu C,
Nazzari AF,
Pegu A,
Shen CH,
Becker JE,
Bender MF ,
Chan P,
Changela A,
Chaudhary R,
Chen X,
Einav T,
Kwon YD,
Lin BC,
Louder MK,
Merriam JS,
Morano NC,
O'Dell S,
Olia AS,
Rawi R,
Roark RS,
Stephens T,
Teng IT,
Tourtellott-Fogt E,
Wang S ,
Yang ES,
Shapiro L,
Tsybovsky Y,
Doria-Rose NA,
Casellas R,
Kwong PD
(2024) Adv Sci , 11 , e2309268 - e2309268
,
Zhou T ,
McKee K,
Zhang B,
Liu C,
Nazzari AF,
Pegu A,
Shen CH,
Becker JE,
Bender MF ,
Chan P,
Changela A,
Chaudhary R,
Chen X,
Einav T,
Kwon YD,
Lin BC,
Louder MK,
Merriam JS,
Morano NC,
O'Dell S,
Olia AS,
Rawi R,
Roark RS,
Stephens T,
Teng IT,
Tourtellott-Fogt E,
Wang S ,
Yang ES,
Shapiro L,
Tsybovsky Y,
Doria-Rose NA,
Casellas R,
Kwong PD
(2024) Adv Sci , 11 , e2309268 - e2309268
Grant Support: