EMD-41409

Single-particle
5.48 Å
EMD-41409
3D View Gallery
Deposition: 01/08/2023
Map released: 22/05/2024
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41409

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of PCSK9 mimic HIT01-K21Q-R218E with AMG145 Fab

EMD-41409

Single-particle
5.48 Å
EMD-41409
3D View Gallery
Deposition: 01/08/2023
Map released: 22/05/2024
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: HIT01-K21Q-R218E with AMG145 Fab

Deposition Authors: Cheng J, Kwong PD
Cholesterol reduction by immunization with a PCSK9 mimic.
Zhang B, Chuang GY, Biju A, Biner D, Cheng J, Wang Y, Bao S, Chao CW, Lei H, Liu T, Nazzari AF, Yang Y, Zhou T, Chen SJ, Chen X, Kong WP, Ou L, Parchment DK , Sarfo EK, SiMa H, Todd JP, Wang S, Woodward RA, Cheng C, Rawi R, Mascola JR, Kwong PD
(2024) Cell Rep , 43 , 114285 - 114285
PUBMED: 38819987
DOI: doi:10.1016/j.celrep.2024.114285
ISSN: 2211-1247