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EMD-41363
Cryo-EM structure of DDB1deltaB-DDA1-DCAF5
EMD-41363
Single-particle2.63 Å
Deposition: 26/07/2023Map released: 03/04/2024
Last modified: 17/04/2024
Sample Organism:
Homo sapiens
Sample: Complex of DDB1deltaB-DDA1-DCAF5
Fitted models: 8tl6
Deposition Authors: Yue H, Hunkeler M
,
Roy Burman SS ,
Fischer ES
Sample: Complex of DDB1deltaB-DDA1-DCAF5
Fitted models: 8tl6
Deposition Authors: Yue H, Hunkeler M
,
Roy Burman SS ,
Fischer ES
Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.
Radko-Juettner S,
Yue H,
Myers JA ,
Carter RD ,
Robertson AN ,
Mittal P ,
Zhu Z,
Hansen BS ,
Donovan KA ,
Hunkeler M ,
Rosikiewicz W ,
Wu Z,
McReynolds MG ,
Roy Burman SS ,
Schmoker AM,
Mageed N ,
Brown SA,
Mobley RJ,
Partridge JF ,
Stewart EA ,
Pruett-Miller SM ,
Nabet B ,
Peng J ,
Gray NS ,
Fischer ES ,
Roberts CWM
(2024) Nature , 628 , 442 - 449
,
Carter RD ,
Robertson AN ,
Mittal P ,
Zhu Z,
Hansen BS ,
Donovan KA ,
Hunkeler M ,
Rosikiewicz W ,
Wu Z,
McReynolds MG ,
Roy Burman SS ,
Schmoker AM,
Mageed N ,
Brown SA,
Mobley RJ,
Partridge JF ,
Stewart EA ,
Pruett-Miller SM ,
Nabet B ,
Peng J ,
Gray NS ,
Fischer ES ,
Roberts CWM
(2024) Nature , 628 , 442 - 449
Grant Support:
- The Mark Foundation: 6331505 (United States)