Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-41297

Single-particle
3.6 Å
EMD-41297
3D View Gallery
Deposition: 19/07/2023
Map released: 22/01/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41297
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8tio summary report (pdf.gz) Map and 8tio FULL report (pdf.gz)
EMICSS annotations (xml)

Human ACKR3 with C tail extended by 12 glycines phosphorylated by GRK5 in complex with Arrestin2 reconstructed without receptor/micelle

EMD-41297

Single-particle
3.6 Å
EMD-41297
3D View Gallery
Deposition: 19/07/2023
Map released: 22/01/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bos taurus, synthetic construct, Homo sapiens
Sample: human ACKR3 with C tail extended by 12 glycines phosphorylated by GRK5 in complex with Arrestin2 reconstructed without receptor/micelle
Fitted models: 8tio

Deposition Authors: Chen Q , Tesmer JJG
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Chen Q , Schafer CT , Mukherjee S , Wang K , Gustavsson M , Fuller JR , Tepper K, Lamme TD , Aydin Y , Agrawal P, Terashi G , Yao XQ, Kihara D , Kossiakoff AA , Handel TM , Tesmer JJG
(2025) Nature , 643 , 280 - 287
PUBMED: 40399676
DOI: doi:10.1038/s41586-025-09024-9
ISSN: 1476-4687
ASTM: NATUAS