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EMD-41289
Human ACKR3 phosphorylated by GRK2 in complex with Arrestin2 in nanodisc
EMD-41289
Single-particle3.0 Å
Deposition: 19/07/2023Map released: 22/01/2025
Last modified: 09/07/2025
Sample Organism:
synthetic construct,
Bos taurus,
Homo sapiens
Sample: human ACKR3 phosphorylated by GRK2 in complex with Arrestin2 in nanodisc
Fitted models: 8tii
Deposition Authors: Chen Q
,
Tesmer JJG
Sample: human ACKR3 phosphorylated by GRK2 in complex with Arrestin2 in nanodisc
Fitted models: 8tii
Deposition Authors: Chen Q
,
Tesmer JJG
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Chen Q
,
Schafer CT
,
Mukherjee S
,
Wang K
,
Gustavsson M
,
Fuller JR
,
Tepper K,
Lamme TD
,
Aydin Y
,
Agrawal P,
Terashi G
,
Yao XQ,
Kihara D
,
Kossiakoff AA
,
Handel TM
,
Tesmer JJG
(2025) Nature , 643 , 280 - 287
,
Schafer CT
,
Mukherjee S
,
Wang K
,
Gustavsson M
,
Fuller JR
,
Tepper K,
Lamme TD
,
Aydin Y
,
Agrawal P,
Terashi G
,
Yao XQ,
Kihara D
,
Kossiakoff AA
,
Handel TM
,
Tesmer JJG
(2025) Nature , 643 , 280 - 287
Grant Support:
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA254402 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM117372 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI161880 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA221289 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA023168 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM137505 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): HL071818 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA023168 (United States)
- Walther Cancer Foundation: (United States)
- Robertson Foundation/Cancer Research Institute: Irvington Postdoctoral Fellowship (United States)
- VILLUM FONDEN: 00025326 (Denmark)
- Ralph W. and Grace M. Showalter Research Trust: 4480108 (United States)
