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EMD-41275

Single-particle
3.25 Å
EMD-41275
3D View Gallery
Deposition: 18/07/2023
Map released: 24/07/2024
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41275
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8thz summary report (pdf.gz) Map and 8thz FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2

EMD-41275

Single-particle
3.25 Å
EMD-41275
3D View Gallery
Deposition: 18/07/2023
Map released: 24/07/2024
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Hepacivirus C
Sample: Ternary complex of CBH7-E2-HC84.26
Fitted models: 8thz

Deposition Authors: Shahid S, Jiang L, Liu Y, Hasan SS , Mariuzza RA
Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers.
Shahid S, Karade SS, Hasan SS , Yin R , Jiang L, Liu Y, Felbinger N, Kulakova L, Toth EA , Keck ZY, Foung SKH , Fuerst TR , Pierce BG , Mariuzza RA
(2025) Commun Biol , 8 , 825 - 825
PUBMED: 40442315
DOI: doi:10.1038/s42003-025-08239-w
ISSN: 2399-3642