EMD-41269

Single-particle
3.12 Å
EMD-41269
3D View Gallery
Deposition: 17/07/2023
Map released: 25/10/2023
Last modified: 08/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41269

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8thr summary report (pdf.gz) Map-8thr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to Tetrabenazine in an occluded conformation

EMD-41269

Single-particle
3.12 Å
EMD-41269
3D View Gallery
Deposition: 17/07/2023
Map released: 25/10/2023
Last modified: 08/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Vicugna pacos
Sample: Human VMAT2 complexed with Tetrabenazine
Fitted models: 8thr

Deposition Authors: Dalton MP , Coleman JA
Structural mechanisms for VMAT2 inhibition by tetrabenazine.
Dalton MP , Cheng MH , Bahar I, Coleman JA
(2024) eLife , 12
PUBMED: 38517752
DOI: doi:10.7554/eLife.91973
ISSN: 2050-084X
Grant Support: