EMD-41261

Single-particle
2.9 Å
EMD-41261
3D View Gallery
Deposition: 16/07/2023
Map released: 22/11/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41261

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8thg summary report (pdf.gz) Map-8thg FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Nav1.7 with RLZ

EMD-41261

Single-particle
2.9 Å
EMD-41261
3D View Gallery
Deposition: 16/07/2023
Map released: 22/11/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human voltage-gated sodium channel Nav1.7 with beta subunits
Fitted models: 8thg

Deposition Authors: Fan X , Huang J , Yan N
Dual-pocket inhibition of Na v channels by the antiepileptic drug lamotrigine.
Huang J , Fan X , Jin X, Teng L, Yan N
(2023) PNAS , 120 , e2309773120 - e2309773120
PUBMED: 37782796
DOI: doi:10.1073/pnas.2309773120
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: