EMD-41138

Single-particle
3.05 Å
EMD-41138
3D View Gallery
Deposition: 27/06/2023
Map released: 17/01/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41138

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8tan summary report (pdf.gz) Map-8tan FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM structure of MFRV-VILP bound to IGF1Rzip

EMD-41138

Single-particle
3.05 Å
EMD-41138
3D View Gallery
Deposition: 27/06/2023
Map released: 17/01/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mandarin fish ranavirus, Homo sapiens
Sample: 1:2 complex of MFRV-VILP bound to IGF1Rzip
Fitted models: 8tan

Deposition Authors: Kirk NS
A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Chrudinova M, Kirk NS , Chuard A, Venugopal H, Zhang F, Lubos M , Gelfanov V, Panikova T, Zakova L , Cutone J, Mojares M, DiMarchi R, Jiracek J , Altindis E
(2024) Mol Metab , 80 , 101863 - 101863
PUBMED: 38182007
DOI: doi:10.1016/j.molmet.2023.101863
ISSN: 2212-8778