EMD-41136

Single-particle
3.1 Å
EMD-41136
3D View Gallery
Deposition: 27/06/2023
Map released: 06/09/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41136

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8tai summary report (pdf.gz) Map-8tai FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TMEM16F, with Calcium and PIP2, no inhibitor, Cl2

EMD-41136

Single-particle
3.1 Å
EMD-41136
3D View Gallery
Deposition: 27/06/2023
Map released: 06/09/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: 16F
Fitted models: 8tai

Deposition Authors: Wu H, Feng S, Cheng Y
Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase.
Feng S, Puchades C , Ko J , Wu H, Chen Y, Figueroa EE , Gu S, Han TW, Ho B, Cheng T, Li J, Shoichet B, Jan YN , Cheng Y , Jan LY
(2023) Nat Commun , 14 , 4874 - 4874
PUBMED: 37573365
DOI: doi:10.1038/s41467-023-40410-x
ISSN: 2041-1723
Grant Support: