Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-41082

Single-particle
2.95 Å
EMD-41082
3D View Gallery
Deposition: 18/06/2023
Map released: 13/09/2023
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41082
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8t6v summary report (pdf.gz) Map and 8t6v FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)

EMD-41082

Single-particle
2.95 Å
EMD-41082
3D View Gallery
Deposition: 18/06/2023
Map released: 13/09/2023
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dimeric anion exchanger 1 (SLC4A1)
Fitted models: 8t6v

Deposition Authors: Capper MJ , Zilberg G, Mathiharan YK , Yang S , Stone AC , Wacker D
Substrate binding and inhibition of the anion exchanger 1 transporter.
Capper MJ , Yang S , Stone AC , Vatansever S, Zilberg G, Mathiharan YK , Habib R, Hutchinson K, Zhao Y, Schlessinger A , Mezei M , Osman R, Zhang B, Wacker D
(2023) Nat Struct Mol Biol , 30 , 1495 - 1504
PUBMED: 37679563
DOI: doi:10.1038/s41594-023-01085-6
ISSN: 1545-9985