EMD-41072
Human leukocyte antigen bound by two alloreactive antibody Fabs
EMD-41072
Single-particle3.14 Å
Deposition: 16/06/2023Map released: 25/12/2024
Last modified: 14/01/2026
Sample Organism:
Homo sapiens
Sample: L02/M07/A*01:01 complex
Fitted models: 8t6m
Deposition Authors: Kizziah JL, Killian JT, Diaz-Avalos R, Qiu S, Yang G, Green T, Lund FE
Sample: L02/M07/A*01:01 complex
Fitted models: 8t6m
Deposition Authors: Kizziah JL, Killian JT, Diaz-Avalos R, Qiu S, Yang G, Green T, Lund FE
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients.
Killian Jr JT,
King RG,
Lucander ACK,
Kizziah JL,
Fucile CF,
Diaz-Avalos R,
Qiu S,
Silva-Sanchez A,
Mousseau BJ,
Macon KJ,
Callahan AR,
Yang G,
Hossain ME,
Akther J,
Good DB,
Kelso S,
Houp JA,
Rosenblum F,
Porrett PM 
,
Ong SC,
Kumar V,
Saphire EO,
Kearney JF,
Randall TD,
Rosenberg AF,
Green TJ,
Lund FE
(2025) Immunity , 58 , 3040 - 3060.e12
,
Ong SC,
Kumar V,
Saphire EO,
Kearney JF,
Randall TD,
Rosenberg AF,
Green TJ,
Lund FE
(2025) Immunity , 58 , 3040 - 3060.e12
Grant Support:
- National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK): T32DK007545 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): T32AI007051 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): U19AI142737 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): S10OD024978 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): P30CA013148 (United States)