EMD-40953

Single-particle
3.45 Å
EMD-40953
3D View Gallery
Deposition: 01/06/2023
Map released: 17/01/2024
Last modified: 31/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40953

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8t13 summary report (pdf.gz) Map-8t13 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of DENV2 NS5 in complex with human STAT2 with the N-terminal domain of STAT2 disordered

EMD-40953

Single-particle
3.45 Å
EMD-40953
3D View Gallery
Deposition: 01/06/2023
Map released: 17/01/2024
Last modified: 31/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Dengue virus type 2
Sample: Complex of DENV2 NS5 with human STAT2
Fitted models: 8t13

Deposition Authors: Biswal M , Lu J , Song J
A conformational selection mechanism of flavivirus NS5 for species-specific STAT2 inhibition.
Biswal M , Yao W, Lu J , Chen J, Morrison J, Hai R , Song J
(2024) Commun Biol , 7 , 76 - 76
PUBMED: 38195857
DOI: doi:10.1038/s42003-024-05768-8
ISSN: 2399-3642