EMD-40820

Single-particle
4.32 Å
EMD-40820
3D View Gallery
Deposition: 18/05/2023
Map released: 14/02/2024
Last modified: 14/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40820

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8swk summary report (pdf.gz) Map-8swk FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of NLRP3 closed hexamer

EMD-40820

Single-particle
4.32 Å
EMD-40820
3D View Gallery
Deposition: 18/05/2023
Map released: 14/02/2024
Last modified: 14/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NLRP3 open octamer complex
Fitted models: 8swk

Deposition Authors: Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S
(2024) Nat Commun
ISSN: 2041-1723
Grant Support: