EMD-40753

Single-particle
2.4 Å
EMD-40753
3D View Gallery
Deposition: 09/05/2023
Map released: 07/02/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40753

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8st0 summary report (pdf.gz) Map-8st0 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The 2alpha3beta stoichiometry of full-length human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine

EMD-40753

Single-particle
2.4 Å
EMD-40753
3D View Gallery
Deposition: 09/05/2023
Map released: 07/02/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: A complex of three Fab fragments with the 2alpha3beta stoichiometry of the full-length human alpha4beta2 nicotinic receptor bound to acetylcholine
Fitted models: 8st0

Deposition Authors: Kang G , Hibbs RE
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Mazzaferro S , Kang G , Natarajan K , Hibbs RE , Sine SM
(2024) Br.J.Pharmacol. , 181 , 1973 - 1992
PUBMED: 38454578
DOI: doi:10.1111/bph.16321
ISSN: 0007-1188
ASTM: BJPCBH