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EMD-40752

Single-particle
2.64 Å
EMD-40752
3D View Gallery
Deposition: 09/05/2023
Map released: 07/02/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40752
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ssz summary report (pdf.gz) Map and 8ssz FULL report (pdf.gz)
EMICSS annotations (xml)

The 2alpha3beta stoichiometry of full-length human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine and calcium

EMD-40752

Single-particle
2.64 Å
EMD-40752
3D View Gallery
Deposition: 09/05/2023
Map released: 07/02/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: A complex of three Fab fragments with the 2alpha3beta stoichiometry of the full-length human alpha4beta2 nicotinic receptor bound to acetylcholine and calcium
Fitted models: 8ssz

Deposition Authors: Kang G , Hibbs RE
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Mazzaferro S , Kang G , Natarajan K , Hibbs RE , Sine SM
(2024) Br.J.Pharmacol. , 181 , 1973 - 1992
PUBMED: 38454578
DOI: doi:10.1111/bph.16321
ISSN: 0007-1188
ASTM: BJPCBH