EMD-40732

Single-particle
2.73 Å
EMD-40732
3D View Gallery
Deposition: 05/05/2023
Map released: 15/05/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40732

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8sri summary report (pdf.gz) Map-8sri FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state

EMD-40732

Single-particle
2.73 Å
EMD-40732
3D View Gallery
Deposition: 05/05/2023
Map released: 15/05/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Salpingoeca rosetta
Sample: TRPM2 chanzyme (E1114A) incubated with Magnesium and ADP-ribose for 5s; ADP-ribose intact; closed state
Fitted models: 8sri

Deposition Authors: Huang Y, Kumar S , Lu W , Du J
Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Huang Y, Kumar S , Lee J , Lu W , Du J
(2024) Nat Struct Mol Biol , 31 , 1509 - 1521
PUBMED: 38773335
DOI: doi:10.1038/s41594-024-01316-4
ISSN: 1545-9985