EMD-40716

Single-particle
3.53 Å
EMD-40716
3D View Gallery
Deposition: 05/05/2023
Map released: 06/09/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40716

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8sr0 summary report (pdf.gz) Map-8sr0 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined

EMD-40716

Single-particle
3.53 Å
EMD-40716
3D View Gallery
Deposition: 05/05/2023
Map released: 06/09/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: therapeutic antibody (favezelimab) bound to human LAG3
Fitted models: 8sr0

Deposition Authors: Mishra AK , Shahid S, Karade SS, Mariuzza RA
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Mishra AK , Shahid S, Karade SS, Agnihotri P, Kolesnikov A, Hasan SS, Mariuzza RA
(2023) Structure , 31 , 1149
PUBMED: 37619561
DOI: doi:10.1016/j.str.2023.07.013
ISSN: 0969-2126
ASTM: STRUE6