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EMD-40557
Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43)
EMD-40557
Single-particle2.93 Å
Deposition: 18/04/2023Map released: 14/06/2023
Last modified: 11/12/2024
Sample Organism:
Influenza A virus,
synthetic construct
Sample: Influenza HA (Iowa43) bound to RFdiffusion designed minibinder, HA_20
Fitted models: 8sk7
Deposition Authors: Borst AJ
,
Bennett NR
Sample: Influenza HA (Iowa43) bound to RFdiffusion designed minibinder, HA_20
Fitted models: 8sk7
Deposition Authors: Borst AJ
,
Bennett NR
De novo design of protein structure and function with RFdiffusion.
Watson JL ,
Juergens D ,
Bennett NR ,
Trippe BL,
Yim J ,
Eisenach HE,
Ahern W ,
Borst AJ ,
Ragotte RJ,
Milles LF ,
Wicky BIM ,
Hanikel N ,
Pellock SJ ,
Courbet A ,
Sheffler W,
Wang J,
Venkatesh P,
Sappington I,
Torres SV,
Lauko A,
De Bortoli V,
Mathieu E,
Ovchinnikov S ,
Barzilay R,
Jaakkola TS ,
DiMaio F,
Baek M ,
Baker D
(2023) Nature , 620 , 1089 - 1100
,
Juergens D ,
Bennett NR ,
Trippe BL,
Yim J ,
Eisenach HE,
Ahern W ,
Borst AJ ,
Ragotte RJ,
Milles LF ,
Wicky BIM ,
Hanikel N ,
Pellock SJ ,
Courbet A ,
Sheffler W,
Wang J,
Venkatesh P,
Sappington I,
Torres SV,
Lauko A,
De Bortoli V,
Mathieu E,
Ovchinnikov S ,
Barzilay R,
Jaakkola TS ,
DiMaio F,
Baek M ,
Baker D
(2023) Nature , 620 , 1089 - 1100
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)