Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-40468

Subtomogram averaging
16.5 Å
EMD-40468 Deposition: 13/04/2023
Map released: 21/02/2024
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40468

In situ human cardiac thick filament in the relaxed state

EMD-40468

Subtomogram averaging
16.5 Å
EMD-40468 Deposition: 13/04/2023
Map released: 21/02/2024
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: In situ human cardiac thick filament in the relaxed state

Deposition Authors: Chen L , Liu J , Rastegarpouyani H , Janssen PML , Pinto JR , Taylor KA
Structure of mavacamten-free human cardiac thick filaments within the sarcomere by cryoelectron tomography.
Chen L , Liu J , Rastegarpouyani H , Janssen PML , Pinto JR , Taylor KA
(2024) PNAS , 121 , e2311883121 - e2311883121
PUBMED: 38386705
DOI: doi:10.1073/pnas.2311883121
ISSN: 1091-6490
ASTM: PNASA6