EMD-40344

Single-particle
2.5 Å
EMD-40344
3D View Gallery
Deposition: 05/04/2023
Map released: 27/12/2023
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40344

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8scb summary report (pdf.gz) Map-8scb FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Terminating ribosome with SRI-41315

EMD-40344

Single-particle
2.5 Å
EMD-40344
3D View Gallery
Deposition: 05/04/2023
Map released: 27/12/2023
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus, Homo sapiens
Sample: terminating rabbit ribosome
Fitted models: 8scb

Deposition Authors: Yip MCJ , Coelho JPL , Oltion K, Tauton J, Shao S
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.
Coelho JPL , Yip MCJ , Oltion K, Taunton J , Shao S
(2024) Nat Chem Biol , 20 , 877 - 884
PUBMED: 38172604
DOI: doi:10.1038/s41589-023-01521-0
ISSN: 1552-4469