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EMD-40270
Cryo-EM structure of GPR34-Gi complex
EMD-40270
Single-particle3.27 Å
Deposition: 01/04/2023Map released: 04/10/2023
Last modified: 13/11/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Human GPR34 in complex with Gi heterotrimer and scFv16
Fitted models: 8sai
Deposition Authors: Yong XH, Zhao C
,
Yan W,
Shao ZH
Sample: Human GPR34 in complex with Gi heterotrimer and scFv16
Fitted models: 8sai
Deposition Authors: Yong XH, Zhao C
,
Yan W,
Shao ZH
Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Xia A ,
Yong X ,
Zhang C ,
Lin G,
Jia G ,
Zhao C ,
Wang X ,
Hao Y ,
Wang Y,
Zhou P,
Yang X,
Deng Y,
Wu C,
Chen Y,
Zhu J,
Tang X,
Liu J,
Zhang S,
Zhang J,
Xu Z,
Hu Q,
Zhao J,
Yue Y,
Yan W,
Su Z ,
Wei Y,
Zhou R,
Dong H,
Shao Z ,
Yang S
(2023) PNAS , 120 , e2308435120 - e2308435120
,
Yong X ,
Zhang C ,
Lin G,
Jia G ,
Zhao C ,
Wang X ,
Hao Y ,
Wang Y,
Zhou P,
Yang X,
Deng Y,
Wu C,
Chen Y,
Zhu J,
Tang X,
Liu J,
Zhang S,
Zhang J,
Xu Z,
Hu Q,
Zhao J,
Yue Y,
Yan W,
Su Z ,
Wei Y,
Zhou R,
Dong H,
Shao Z ,
Yang S
(2023) PNAS , 120 , e2308435120 - e2308435120
Grant Support: