EMD-40207

Single-particle
3.8 Å
EMD-40207
3D View Gallery
Deposition: 23/03/2023
Map released: 26/06/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40207

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8gls summary report (pdf.gz) Map-8gls FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853

EMD-40207

Single-particle
3.8 Å
EMD-40207
3D View Gallery
Deposition: 23/03/2023
Map released: 26/06/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CFTR
Fitted models: 8gls

Deposition Authors: Liu F, Chen J
Structure-based discovery of CFTR potentiators and inhibitors.
Liu F, Kaplan AL, Levring J, Einsiedel J, Tiedt S, Distler K, Omattage NS, Kondratov IS, Moroz YS, Pietz HL , Irwin JJ, Gmeiner P, Shoichet BK, Chen J
(2024) Cell , 187 , 3712 - 3725.e34
PUBMED: 38810646
DOI: doi:10.1016/j.cell.2024.04.046
ISSN: 1097-4172