EMD-40047

Single-particle
3.2 Å
EMD-40047
3D View Gallery
Deposition: 10/03/2023
Map released: 02/08/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40047

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ghr summary report (pdf.gz) Map-8ghr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human ENPP1 in complex with variable heavy domain VH27.2

EMD-40047

Single-particle
3.2 Å
EMD-40047
3D View Gallery
Deposition: 10/03/2023
Map released: 02/08/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ENPP1-VH27 complex
Fitted models: 8ghr

Deposition Authors: Carozza JA, Wang H, Solomon PE, Wells JA , Li L
Discovery of VH domains that allosterically inhibit ENPP1.
Solomon PE, Bracken CJ , Carozza JA, Wang H, Young EP, Wellner A, Liu CC , Sweet-Cordero EA , Li L , Wells JA
(2024) Nat Chem Biol , 20 , 30 - 41
PUBMED: 37400538
DOI: doi:10.1038/s41589-023-01368-5
ISSN: 1552-4469