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EMD-40000

Single-particle
3.5 Å
EMD-40000
3D View Gallery
Deposition: 08/03/2023
Map released: 06/03/2024
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40000
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8gga summary report (pdf.gz) Map and 8gga FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #16 of 20)

EMD-40000

Single-particle
3.5 Å
EMD-40000
3D View Gallery
Deposition: 08/03/2023
Map released: 06/03/2024
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of beta-2 adrenergic receptor and Gs heterotrimer with GTP
Fitted models: 8gga

Deposition Authors: Papasergi-Scott MM , Skiniotis G
Time-resolved cryo-EM of G-protein activation by a GPCR.
Papasergi-Scott MM , Perez-Hernandez G , Batebi H , Gao Y , Eskici G, Seven AB, Panova O , Hilger D , Casiraghi M, He F , Maul L, Gmeiner P , Kobilka BK , Hildebrand PW , Skiniotis G
(2024) Nature , 629 , 1182 - 1191
PUBMED: 38480881
DOI: doi:10.1038/s41586-024-07153-1
ISSN: 1476-4687
ASTM: NATUAS