EMD-39909

Single-particle
2.96 Å
EMD-39909
3D View Gallery
Deposition: 27/04/2024
Map released: 09/04/2025
Last modified: 09/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39909

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8zbs summary report (pdf.gz) Map-8zbs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with vincristine)

EMD-39909

Single-particle
2.96 Å
EMD-39909
3D View Gallery
Deposition: 27/04/2024
Map released: 09/04/2025
Last modified: 09/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with vincristine)
Fitted models: 8zbs

Deposition Authors: Xie Z , Long F
Structural basis for the reversal of human MRP4-mediated multidrug resistance by lapatinib.
Xie Z , Lv J, Huang W, Wu Z, Zhu R, Deng Z, Long F
(2025) Cell Rep , 44 , 115466 - 115466
PUBMED: 40138312
DOI: doi:10.1016/j.celrep.2025.115466
ISSN: 2211-1247