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EMD-39819

Single-particle
3.42 Å
EMD-39819
3D View Gallery
Deposition: 20/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39819
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8z7l summary report (pdf.gz) Map and 8z7l FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of S-bottom)

EMD-39819

Single-particle
3.42 Å
EMD-39819
3D View Gallery
Deposition: 20/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused on S-bottom)
Fitted models: 8z7l

Deposition Authors: Liu Z, Xing L
Early fusion intermediate of ACE2-using coronavirus spike acting as an antiviral target.
Xing L, Liu Z, Wang X, Liu Q, Xu W, Mao Q, Zhang X, Hao A, Xia S, Liu Z, Sun L, Zhang G, Wang Q, Chen Z, Jiang S, Sun L, Lu L
(2025) Cell , 188 , 1297 - 1314.e24
PUBMED: 39889696
DOI: doi:10.1016/j.cell.2025.01.012
ISSN: 1097-4172