EMD-39813

Single-particle
3.06 Å
EMD-39813
3D View Gallery
Deposition: 20/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39813

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8z7g summary report (pdf.gz) Map-8z7g FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of intact S2)

EMD-39813

Single-particle
3.06 Å
EMD-39813
3D View Gallery
Deposition: 20/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused on intact S2)
Fitted models: 8z7g

Deposition Authors: Liu Z, Xing L
Early fusion intermediate of ACE2-using coronavirus spike acting as an antiviral target.
Xing L, Liu Z, Wang X, Liu Q, Xu W, Mao Q, Zhang X, Hao A, Xia S, Liu Z, Sun L, Zhang G, Wang Q, Chen Z, Jiang S, Sun L, Lu L
(2025) Cell , 188 , 1297 - 1314.e24
PUBMED: 39889696
DOI: doi:10.1016/j.cell.2025.01.012
ISSN: 1097-4172