Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-39756

Single-particle
3.45 Å
EMD-39756
3D View Gallery
Deposition: 16/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39756
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8z3w summary report (pdf.gz) Map and 8z3w FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 D614G S with one ACE2 receptor binding (RB1) in prefusion conformation

EMD-39756

Single-particle
3.45 Å
EMD-39756
3D View Gallery
Deposition: 16/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: D614G spike protein (S) in complex with one ACE2
Fitted models: 8z3w

Deposition Authors: Liu Z, Xing L
Early fusion intermediate of ACE2-using coronavirus spike acting as an antiviral target.
Xing L, Liu Z, Wang X, Liu Q, Xu W, Mao Q, Zhang X, Hao A, Xia S, Liu Z, Sun L, Zhang G, Wang Q, Chen Z, Jiang S, Sun L, Lu L
(2025) Cell , 188 , 1297 - 1314.e24
PUBMED: 39889696
DOI: doi:10.1016/j.cell.2025.01.012
ISSN: 1097-4172