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EMD-39633
Cryo-EM structure of small and dead form SaCas9-RNA-DNA ternary complex (sdCas9)
EMD-39633
Single-particle2.97 Å
Deposition: 31/03/2024Map released: 02/04/2025
Last modified: 16/07/2025
Sample Organism:
synthetic construct,
Staphylococcus aureus
Sample: Cryo-EM structure of Compact SaCas9-RNA-DNA ternary complex
Fitted models: 8ywh
Deposition Authors: Kang ES
,
Kim NH ,
Thach TT ,
Hyun J ,
Kim YH
Sample: Cryo-EM structure of Compact SaCas9-RNA-DNA ternary complex
Fitted models: 8ywh
Deposition Authors: Kang ES
,
Kim NH ,
Thach TT ,
Hyun J ,
Kim YH
Structure-Guided Engineering of Thermodynamically Enhanced SaCas9 for Improved Gene Suppression.
Kang ES ,
Kim NH ,
Lim HK ,
Jeon H ,
Han K ,
No YH ,
Kim K ,
Khaleel ZH ,
Shin D ,
Eom K ,
Nam J,
Lee BS,
Kim HJ,
Suh M,
Lee J,
Thach TT ,
Hyun J ,
Kim YH
(2025) Adv Mater , 37 , e2404680 - e2404680
,
Kim NH ,
Lim HK ,
Jeon H ,
Han K ,
No YH ,
Kim K ,
Khaleel ZH ,
Shin D ,
Eom K ,
Nam J,
Lee BS,
Kim HJ,
Suh M,
Lee J,
Thach TT ,
Hyun J ,
Kim YH
(2025) Adv Mater , 37 , e2404680 - e2404680
Grant Support:
- National Research Foundation (NRF, Korea): NRF-2023R1A2C300573 (Korea, Republic Of)
- National Research Foundation (NRF, Korea): RS-2023-00302458 (Korea, Republic Of)