Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-39594
Cryo-EM structure of CDCA7 bound to nucleosome including hemimethylated CpG site in Widom601 positioning sequence.
EMD-39594
Single-particle3.0 Å
Deposition: 28/03/2024Map released: 31/07/2024
Last modified: 12/03/2025
Sample Organism:
Homo sapiens,
synthetic construct
Sample: CDCA7 bound to nucleosome
Fitted models: 8yv8
Deposition Authors: Kikuchi A
,
Shikimachi R,
Nishiyama A ,
Funabiki H ,
Arita K
Sample: CDCA7 bound to nucleosome
Fitted models: 8yv8
Deposition Authors: Kikuchi A
,
Shikimachi R,
Nishiyama A ,
Funabiki H ,
Arita K
CDCA7 is an evolutionarily conserved hemimethylated DNA sensor in eukaryotes.
Wassing IE ,
Nishiyama A ,
Shikimachi R,
Jia Q ,
Kikuchi A ,
Hiruta M,
Sugimura K,
Hong X,
Chiba Y,
Peng J,
Jenness C,
Nakanishi M,
Zhao L ,
Arita K ,
Funabiki H
(2024) Sci Adv , 10 , eadp5753 - eadp5753
,
Nishiyama A ,
Shikimachi R,
Jia Q ,
Kikuchi A ,
Hiruta M,
Sugimura K,
Hong X,
Chiba Y,
Peng J,
Jenness C,
Nakanishi M,
Zhao L ,
Arita K ,
Funabiki H
(2024) Sci Adv , 10 , eadp5753 - eadp5753