Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-39553

Single-particle
2.93 Å
EMD-39553
3D View Gallery
Deposition: 22/03/2024
Map released: 25/06/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39553
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8yry summary report (pdf.gz) Map and 8yry FULL report (pdf.gz)
EMICSS annotations (xml)

HER3 in complex with FAb Hu3f8

EMD-39553

Single-particle
2.93 Å
EMD-39553
3D View Gallery
Deposition: 22/03/2024
Map released: 25/06/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: complex of Her3 with fab Hu3f8
Fitted models: 8yry

Deposition Authors: Wang M, Li X

DB-1310,a novel HER3-targeting antibody-drug conjugate,shows synergistic antitumor activity with trastuzumab in breast cancer
Li X
To Be Published
Grant Support: