EMD-39497

Single-particle
2.9 Å
EMD-39497
3D View Gallery
Deposition: 19/03/2024
Map released: 24/09/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39497

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8yq6 summary report (pdf.gz) Map-8yq6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of a de novo designed voltage-gated anion channel (dVGAC)

EMD-39497

Single-particle
2.9 Å
EMD-39497
3D View Gallery
Deposition: 19/03/2024
Map released: 24/09/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct
Sample: de novo designed ion channel
Fitted models: 8yq6

Deposition Authors: Lu PL, Zhou C
De novo designed voltage-gated anion channels suppress neuron firing.
Zhou C, Li H, Wang J, Qian C, Xiong H, Chu Z, Shao Q, Li X, Sun S, Sun K, Zhu A, Wang J, Jin X, Yang F, Gamal El-Din TM, Li B, Huang J, Wu K, Lu P
(2025) Cell , 188 , 7495
PUBMED: 41106381
DOI: doi:10.1016/j.cell.2025.09.023
ISSN: 1097-4172