EMD-39365

Single-particle
2.9 Å
EMD-39365
3D View Gallery
Deposition: 04/03/2024
Map released: 13/08/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39365

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ykd summary report (pdf.gz) Map-8ykd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of ADGRG2-Gs complex with NTF nanobody

EMD-39365

Single-particle
2.9 Å
EMD-39365
3D View Gallery
Deposition: 04/03/2024
Map released: 13/08/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Spodoptera, Bos taurus
Sample: Complex of ADGRG2 with nanonody and G protein trimer
Fitted models: 8ykd

Deposition Authors: Huang SM, Sheng-chao G
Development of an allosteric adhesion GPCR nanobody with therapeutic potential.
Zheng Y , Jiang D , Lu Y , Zhang C , Huang SM, Lin H , Zhang D , Guo S, Han J , Chen J , He Y , Zhang M , Gao Y , Guo Y , Wei R , Xia M, Qin Y , Liu Z, Yang F , Ge S, Yi F , Yu X , Lin H , Xiao P , Sun JP , Feng S
(2025) Nat Chem Biol , 21 , 1519 - 1530
PUBMED: 40374856
DOI: doi:10.1038/s41589-025-01896-2
ISSN: 1552-4469