EMD-39253

Single-particle
3.2 Å
EMD-39253
3D View Gallery
Deposition: 26/02/2024
Map released: 05/06/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39253

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ygj summary report (pdf.gz) Map-8ygj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt)

EMD-39253

Single-particle
3.2 Å
EMD-39253
3D View Gallery
Deposition: 26/02/2024
Map released: 05/06/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Streptococcus pyogenes, Moloney murine leukemia virus, Streptococcus pyogenes serotype M1
Sample: SpCas9-MMLV RT-pegRNA-target DNA complex
Fitted models: 8ygj

Deposition Authors: Shuto Y , Nakagawa R, Hoki M, Omura SN , Hirano H, Itoh Y , Nureki O
Structural basis for pegRNA-guided reverse transcription by a prime editor.
Shuto Y , Nakagawa R, Zhu S, Hoki M, Omura SN , Hirano H, Itoh Y , Zhang F , Nureki O
(2024) Nature , 631 , 224 - 231
PUBMED: 38811740
DOI: doi:10.1038/s41586-024-07497-8
ISSN: 1476-4687
ASTM: NATUAS