EMD-39225

Single-particle
2.71 Å
EMD-39225
3D View Gallery
Deposition: 25/02/2024
Map released: 03/09/2025
Last modified: 02/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39225

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8yfo summary report (pdf.gz) Map-8yfo FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

A cryo-EM structure of Ac-LA-PTH-PTH1R-Gs complex

EMD-39225

Single-particle
2.71 Å
EMD-39225
3D View Gallery
Deposition: 25/02/2024
Map released: 03/09/2025
Last modified: 02/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Rattus norvegicus, Lama glama, synthetic construct
Sample: A cryo_EM structure of PTH1R
Fitted models: 8yfo

Deposition Authors: Zhao L , He Q, Yuan Q, Gu Y, He X, Shan H, Wang K, Li Y, Hu W, Wu K, Shen J, Xu HE
Structural basis of PTH1R-beta-arrestin core engagement reveals design principles for G-protein-biased therapeutics.
Zhao LH, He Q, Yuan Q, Zhang M, Zhao GG, Sun J, Hu W, Shan H, Xu HE
(2026) Nat Struct Mol Biol , 33 , 868 - 881
PUBMED: 42115346
DOI: doi:10.1038/s41594-026-01806-7
ISSN: 1545-9985