Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-39011

Single-particle
2.84 Å
EMD-39011
3D View Gallery
Deposition: 03/02/2024
Map released: 06/08/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39011
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y73 summary report (pdf.gz) Map and 8y73 FULL report (pdf.gz)
EMICSS annotations (xml)

positive allosteric modulator(MPAM-15)-bound mu-opioid receptor-Gi complex

EMD-39011

Single-particle
2.84 Å
EMD-39011
3D View Gallery
Deposition: 03/02/2024
Map released: 06/08/2025
Last modified: 06/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Rattus norvegicus, Bos taurus
Sample: positive allosteric modulator(BMS986187)-bound delta-opioid receptor-G complex
Fitted models: 8y73

Deposition Authors: Luo P, Xu Y, Wang Y, Zhuang Y, Xu HE

Structure based design of a positive allosteric modulator of mu-opioid receptor for synergistic analgesia
Luo P, Xu Y, Wang Y, Zhuang Y, Xu HE
To Be Published