EMD-39010

Single-particle
2.65 Å
EMD-39010
3D View Gallery
Deposition: 03/02/2024
Map released: 06/08/2025
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39010
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y72 summary report (pdf.gz) Map and 8y72 FULL report (pdf.gz)
EMICSS annotations (xml)

positive allosteric modulator(BMS986122)-bound mu-opioid receptor-Gi complex

EMD-39010

Single-particle
2.65 Å
EMD-39010
3D View Gallery
Deposition: 03/02/2024
Map released: 06/08/2025
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Rattus norvegicus, Bos taurus
Sample: positive allosteric modulator(BMS986122)-bound mu-opioid receptor-Gi complex
Fitted models: 8y72

Deposition Authors: Luo P, Xu Y, Wang Y, Zhuang Y, Xu HE
Structure-based design of an opioid receptor modulator for enhanced morphine analgesia.
Wang Y, Luo P, Xu H, Zhan L, Sakamoto K, Li M, Wang J, Huang XP, Zhou J, Liu T, Suo Y, Fan W, He X, Xu Y, Cai Y, Wang C, Zhao Y, Dai A, Lai Y, Yuan Q, Hu W, Wu K, Yang D, Cheng X, Lu X, Krumm B, Kenakin T, Zhang J, Roth BL, Gao Z, Xu HE, Zhuang Y
(2026) Sci Adv , 12 , eaea9832 - eaea9832
PUBMED: 41671375
DOI: doi:10.1126/sciadv.aea9832
ISSN: 2375-2548