EMD-38987

Single-particle
2.54 Å
EMD-38987
3D View Gallery
Deposition: 02/02/2024
Map released: 17/04/2024
Last modified: 27/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38987

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8y6i summary report (pdf.gz) Map-8y6i FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc

EMD-38987

Single-particle
2.54 Å
EMD-38987
3D View Gallery
Deposition: 02/02/2024
Map released: 17/04/2024
Last modified: 27/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Multidrug resistance protein
Fitted models: 8y6i

Deposition Authors: Hamaguchi-Suzuki N , Adachi N , Moriya T , Kawasaki M, Suzuki K, Anzai N , Senda T , Murata T
Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules.
Hamaguchi-Suzuki N , Adachi N , Moriya T , Yasuda S, Kawasaki M, Suzuki K, Ogasawara S, Anzai N , Senda T , Murata T
(2024) Biochem Biophys Res Commun , 709 , 149855 - 149855
PUBMED: 38579618
DOI: doi:10.1016/j.bbrc.2024.149855
ISSN: 1090-2104
ASTM: BBRCA9