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EMD-38986

Single-particle
2.49 Å
EMD-38986
3D View Gallery
Deposition: 02/02/2024
Map released: 17/04/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38986
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y6h summary report (pdf.gz) Map and 8y6h FULL report (pdf.gz)
EMICSS annotations (xml)

P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in LMNG detergent

EMD-38986

Single-particle
2.49 Å
EMD-38986
3D View Gallery
Deposition: 02/02/2024
Map released: 17/04/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Multidrug resistance protein
Fitted models: 8y6h

Deposition Authors: Hamaguchi-Suzuki N , Adachi N , Moriya T , Kawasaki M, Suzuki K, Anzai N , Senda T , Murata T
Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules.
Hamaguchi-Suzuki N , Adachi N , Moriya T , Yasuda S, Kawasaki M, Suzuki K, Ogasawara S, Anzai N , Senda T , Murata T
(2024) Biochem Biophys Res Commun , 709 , 149855 - 149855
PUBMED: 38579618
DOI: doi:10.1016/j.bbrc.2024.149855
ISSN: 1090-2104
ASTM: BBRCA9