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EMD-38965
Cryo-EM structure of the C20:0 ceramide-bound FPR2-Gi complex
EMD-38965
Single-particle3.2 Å
Deposition: 01/02/2024Map released: 05/02/2025
Last modified: 18/06/2025
Sample Organism:
Homo sapiens,
synthetic construct
Sample: Cryo-EM structure of the C20:0 ceramide-bound FPR2-Gi complex
Fitted models: 8y63
Deposition Authors: Sun JP
,
Jiang CT,
Kong W ,
Yu X ,
Cai K ,
Guo LL
Sample: Cryo-EM structure of the C20:0 ceramide-bound FPR2-Gi complex
Fitted models: 8y63
Deposition Authors: Sun JP
,
Jiang CT,
Kong W ,
Yu X ,
Cai K ,
Guo LL
Metabolic signaling of ceramides through the FPR2 receptor inhibits adipocyte thermogenesis.
Lin H ,
Ma C ,
Cai K ,
Guo L ,
Wang X ,
Lv L ,
Zhang C ,
Lin J ,
Zhang D ,
Ye C ,
Wang T ,
Huang S ,
Han J ,
Zhang Z ,
Gao J,
Zhang M ,
Pu Z,
Li F ,
Guo Y ,
Zhou X,
Qin C ,
Yi F ,
Yu X ,
Kong W ,
Jiang C ,
Sun JP
(2025) Science , 388 , eado4188 - eado4188
,
Ma C ,
Cai K ,
Guo L ,
Wang X ,
Lv L ,
Zhang C ,
Lin J ,
Zhang D ,
Ye C ,
Wang T ,
Huang S ,
Han J ,
Zhang Z ,
Gao J,
Zhang M ,
Pu Z,
Li F ,
Guo Y ,
Zhou X,
Qin C ,
Yi F ,
Yu X ,
Kong W ,
Jiang C ,
Sun JP
(2025) Science , 388 , eado4188 - eado4188
Grant Support: