EMD-38847

Single-particle
4.2 Å
EMD-38847
3D View Gallery
Deposition: 25/01/2024
Map released: 22/01/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38847
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y1v summary report (pdf.gz) Map and 8y1v FULL report (pdf.gz)
EMICSS annotations (xml)

GluN1b-GluN2D NMDA receptor in complex with competitive antagonist R-CPP and allosteric inhibitor YY-23

EMD-38847

Single-particle
4.2 Å
EMD-38847
3D View Gallery
Deposition: 25/01/2024
Map released: 22/01/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: N-methyl-D-aspartate receptors
Fitted models: 8y1v

Deposition Authors: Zhang JL, Zhu SJ, Guo F
An antidepressant mechanism underlying the allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons.
Zhang J , Duan J , Li W , Wang X, Ren S, Ye L , Liu F , Tian X, Xie Y , Huang Y , Sun Y , Song N , Li T, Cai X , Liu Z , Zhou H , Huang C , Li Y , Zhu S , Guo F
(2025) Sci Adv , 11 , eadq0444 - eadq0444
PUBMED: 40043126
DOI: doi:10.1126/sciadv.adq0444
ISSN: 2375-2548