Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-38847

Single-particle
4.2 Å
EMD-38847
3D View Gallery
Deposition: 25/01/2024
Map released: 22/01/2025
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38847
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y1v summary report (pdf.gz) Map and 8y1v FULL report (pdf.gz)
EMICSS annotations (xml)

GluN1b-GluN2D NMDA receptor in complex with competitive antagonist R-CPP and allosteric inhibitor YY-23

EMD-38847

Single-particle
4.2 Å
EMD-38847
3D View Gallery
Deposition: 25/01/2024
Map released: 22/01/2025
Last modified: 22/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: N-methyl-D-aspartate receptors
Fitted models: 8y1v

Deposition Authors: Zhang JL , Zhu SJ, Guo F

A novel antidepressant acting via allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons
Zhang JL , Zhu SJ, Fei G
To Be Published