EMD-38677

Single-particle
2.9 Å
EMD-38677
3D View Gallery
Deposition: 13/01/2024
Map released: 15/01/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38677

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8xum summary report (pdf.gz) Map-8xum FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of LGR4 with RSPO2

EMD-38677

Single-particle
2.9 Å
EMD-38677
3D View Gallery
Deposition: 13/01/2024
Map released: 15/01/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Camelus bactrianus
Sample: structure of LGR4 with RSPO2
Fitted models: 8xum

Deposition Authors: Wang L , Geng Y
Cryo-EM structure of the full-length LGR4-RSPOs complex and a targeting nanobody for anti-obesity therapy.
Zhang Z, Wang L , Qiao H , Jiang H , Guo S, Li Y, Zhang N, Geng T, Cui Q, Lan Z, Hong J, Gu W , Liu R , Ning G, Li J , Wang J , Geng Y
(2025) Nat Commun , 16 , 8406 - 8406
PUBMED: 40998774
DOI: doi:10.1038/s41467-025-63410-5
ISSN: 2041-1723
Grant Support: