Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-38630

Single-particle
3.0 Å
EMD-38630 Deposition: 10/01/2024
Map released: 10/07/2024
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38630

Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)

EMD-38630

Single-particle
3.0 Å
EMD-38630 Deposition: 10/01/2024
Map released: 10/07/2024
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 80S ribosome with tigecycline, E-tRNA and CCDC124
Fitted models: 8xsy

Deposition Authors: Li X, Wang M, Cheng J
Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Li X, Wang M, Denk T , Buschauer R, Li Y, Beckmann R , Cheng J
(2024) Nat Commun , 15 , 5481 - 5481
PUBMED: 38942792
DOI: doi:10.1038/s41467-024-49797-7
ISSN: 2041-1723
Grant Support: