Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-38607

Single-particle
3.13 Å
EMD-38607
3D View Gallery
Deposition: 07/01/2024
Map released: 07/05/2025
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38607
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8xrm summary report (pdf.gz) Map and 8xrm FULL report (pdf.gz)
EMICSS annotations (xml)

RNA polymerase II elongation complex with DSIF, SPT6, and ELOF1 transcribing genomic DNA extracted from human nuclei

EMD-38607

Single-particle
3.13 Å
EMD-38607
3D View Gallery
Deposition: 07/01/2024
Map released: 07/05/2025
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: RNA polymerase II complexes isolated from HeLa cell nuclei
Fitted models: 8xrm

Deposition Authors: Kujirai T , Kato J, Yamamoto K, Hirai S, Negishi L , Ogasawara M, Takizawa Y , Kurumizaka H
Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis.
Kujirai T , Kato J, Yamamoto K, Hirai S, Fujii T, Maehara K , Harada A , Negishi L , Ogasawara M, Yamaguchi Y , Ohkawa Y , Takizawa Y , Kurumizaka H
(2025) Nat Commun , 16 , 4724 - 4724
PUBMED: 40436841
DOI: doi:10.1038/s41467-025-59580-x
ISSN: 2041-1723