EMD-38223

Single-particle
3.0 Å
EMD-38223
3D View Gallery
Deposition: 06/12/2023
Map released: 11/06/2025
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38223
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8xbm summary report (pdf.gz) Map and 8xbm FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of Cx43/GJA1 gap junction intercellular channel in complex with diC8-PIP2

EMD-38223

Single-particle
3.0 Å
EMD-38223
3D View Gallery
Deposition: 06/12/2023
Map released: 11/06/2025
Last modified: 11/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dodecameric complex of human Cx43-M257 in lipid nanodiscs (POPE) in the presence of diC8-PIP2 (16-fold molar excess)
Fitted models: 8xbm

Deposition Authors: Lee HJ , Cha HJ , Woo JS

PIP2-dependent conformational changes and stabilization of cytoplasmic loop in Cx43/GJA1 gap junction channel
Lee HJ , Cha HJ , Woo JS
To Be Published