EMD-38059

Single-particle
2.9 Å
EMD-38059
3D View Gallery
Deposition: 16/11/2023
Map released: 29/05/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38059

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8x52 summary report (pdf.gz) Map-8x52 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human gamma-secretase in complex with Abeta49

EMD-38059

Single-particle
2.9 Å
EMD-38059
3D View Gallery
Deposition: 16/11/2023
Map released: 29/05/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human gamma-secretase in complex with Abeta49
Fitted models: 8x52

Deposition Authors: Guo X , Yan C , Lei J , Zhou R , Shi Y , Jia B, Jing D, Yan C , Lei J , Zhou R , Shi Y
Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Guo X , Li H , Yan C , Lei J , Zhou R , Shi Y
(2024) Science , 384 , 1091 - 1095
PUBMED: 38843321
DOI: doi:10.1126/science.adn5820
ISSN: 1095-9203
ASTM: SCIEAS