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EMD-37946
Cryo-EM structure of prefusion-stabilized RSV F (DS-Cav1 strain: A2) in complex with nAb 5B11 (localized refinement)
EMD-37946
Single-particle3.13 Å
Deposition: 01/11/2023Map released: 06/11/2024
Last modified: 04/06/2025
Sample Organism:
Mus musculus,
Human respiratory syncytial virus A2
Sample: RSV A2 preF in complex with mAb 5B11
Fitted models: 8wz4
Deposition Authors: Liu L, Sun H, Sun Y, Zheng Q
,
Li S ,
Zheng Z ,
Xia N
Sample: RSV A2 preF in complex with mAb 5B11
Fitted models: 8wz4
Deposition Authors: Liu L, Sun H, Sun Y, Zheng Q
,
Li S ,
Zheng Z ,
Xia N
A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein.
Sun Y,
Liu L,
Qiang H,
Sun H,
Jiang Y ,
Ren L,
Jiang Z,
Lei S,
Chen L,
Wang Y,
Lin X,
Wang G,
Huang Y,
Fu Y,
Shi Y,
Chen X,
Yu H,
Li S ,
Luo W ,
Liu E,
Zheng Q ,
Zheng Z ,
Xia N
(2024) Nat Commun , 15 , 10085 - 10085
,
Ren L,
Jiang Z,
Lei S,
Chen L,
Wang Y,
Lin X,
Wang G,
Huang Y,
Fu Y,
Shi Y,
Chen X,
Yu H,
Li S ,
Luo W ,
Liu E,
Zheng Q ,
Zheng Z ,
Xia N
(2024) Nat Commun , 15 , 10085 - 10085
Grant Support:
- Not funded: (China)