Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-37517
Local refinement of RBD-ACE2
EMD-37517
Single-particle2.9 Å
Deposition: 22/09/2023Map released: 28/02/2024
Last modified: 23/07/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: RBD complexed with human ACE2
Fitted models: 8wgw
Deposition Authors: Wei X
,
Zhang Z
Sample: RBD complexed with human ACE2
Fitted models: 8wgw
Deposition Authors: Wei X
,
Zhang Z
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
He X ,
Zhang X,
Wu B,
Deng J,
Zhang Y ,
Zhu A,
Yuan Y,
Lin Y,
Chen A,
Feng J,
Wang X,
Wu S,
Liu Y,
Liu J,
Wang Y,
Li R,
Liang C,
Yuan Q,
Liang Y,
Fang Q,
Xi Z ,
Li W,
Liang L,
Zhang Z,
Tang H,
Peng Y,
Ke C,
Ma X ,
Cai W ,
Pan T,
Liu B,
Deng K ,
Chen J ,
Zhao J ,
Wei X ,
Chen R ,
Zhang Y ,
Zhang H
(2024) Nat Immunol , 25 , 622 - 632
,
Zhang X,
Wu B,
Deng J,
Zhang Y ,
Zhu A,
Yuan Y,
Lin Y,
Chen A,
Feng J,
Wang X,
Wu S,
Liu Y,
Liu J,
Wang Y,
Li R,
Liang C,
Yuan Q,
Liang Y,
Fang Q,
Xi Z ,
Li W,
Liang L,
Zhang Z,
Tang H,
Peng Y,
Ke C,
Ma X ,
Cai W ,
Pan T,
Liu B,
Deng K ,
Chen J ,
Zhao J ,
Wei X ,
Chen R ,
Zhang Y ,
Zhang H
(2024) Nat Immunol , 25 , 622 - 632
Grant Support: