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EMD-37516
BA.2(S375) Spike (S6P)/hACE2 complex
EMD-37516
Single-particle2.92 Å
Deposition: 22/09/2023Map released: 28/02/2024
Last modified: 23/07/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: BA.2(S375) Spike (S6P)/hACE2 complex
Fitted models: 8wgv
Deposition Authors: Wei X
,
Zhang Z
Sample: BA.2(S375) Spike (S6P)/hACE2 complex
Fitted models: 8wgv
Deposition Authors: Wei X
,
Zhang Z
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
He X ,
Zhang X,
Wu B,
Deng J,
Zhang Y ,
Zhu A,
Yuan Y,
Lin Y,
Chen A,
Feng J,
Wang X,
Wu S,
Liu Y,
Liu J,
Wang Y,
Li R,
Liang C,
Yuan Q,
Liang Y,
Fang Q,
Xi Z ,
Li W,
Liang L,
Zhang Z,
Tang H,
Peng Y,
Ke C,
Ma X ,
Cai W ,
Pan T,
Liu B,
Deng K ,
Chen J ,
Zhao J ,
Wei X ,
Chen R ,
Zhang Y ,
Zhang H
(2024) Nat Immunol , 25 , 622 - 632
,
Zhang X,
Wu B,
Deng J,
Zhang Y ,
Zhu A,
Yuan Y,
Lin Y,
Chen A,
Feng J,
Wang X,
Wu S,
Liu Y,
Liu J,
Wang Y,
Li R,
Liang C,
Yuan Q,
Liang Y,
Fang Q,
Xi Z ,
Li W,
Liang L,
Zhang Z,
Tang H,
Peng Y,
Ke C,
Ma X ,
Cai W ,
Pan T,
Liu B,
Deng K ,
Chen J ,
Zhao J ,
Wei X ,
Chen R ,
Zhang Y ,
Zhang H
(2024) Nat Immunol , 25 , 622 - 632
Grant Support: